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Researchers based this new study on data they obtained from a large U. insurance database to assess rotavirus vaccine coverage and its impact on health care use and treatment costs for diarrhea-related illness in children under 5 years old. They evaluated data from 2001 to 2009, and assessed direct benefits to vaccinated children and indirect protective benefits to unvaccinated children. Estimated national declines in health care use and treatment costs for children below the age of 5 years in the U. The investigations show that by the end of 2008, 73% of children 12 months or younger, 64 % of 1-year-olds, and 8% of 2 to 4-year-olds had received at least one dose of rotavirus vaccine. Pre-vaccine levels in children under 5 years old resulted in a dramatic 75% decrease in rotavirus-related hospitalizations in 2007-2008 and a 60% decline for 2008-2009 respectively. During the 2008 and 2009 rotavirus seasons (January to June) vaccinated children had 44 to 58% fewer diarrhea-related hospitalizations and 37 to 48% fewer emergency room visits for diarrhea compared with children who were not vaccinated. Compared with pre-vaccine levels, children who were not vaccinated also had a substantial decline in using health care during the 2008 rotavirus season-showing indirect protective benefits. Researchers calculated, that approximately 65,000 hospitalizations of children under the age of 5 years were prevented from 2007 to 2009 nationally, resulting in health care cost savings of about $278 million.

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Mark Pallansch, director of CDC's Division of Viral Diseases, concluded: This study provides more evidence that vaccinating against rotavirus substantially reduces suffering and health care costs for this common childhood illness. As more children get vaccinated against rotavirus, we expect to see even greater reductions in disease among all age groups. Written by Petra Rattue View drug information on Rotarix; Rotateq. An intensive program of handwashing education and promotion in Pakistan decreased the incidence of diarrhea by more than 50 percent among children, according to a study in the June 2 issue of The Journal of the American Medical Association (JAMA), a theme issue on Global Health. of the Centers for Disease Control and Prevention, Atlanta, presented the findings of the study today at a JAMA media briefing at the National Press Club in Washington, D. Nearly 2 million children worldwide die annually from diarrheal disease, according to background information in the article.

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